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http://dspace.mediu.edu.my:8181/xmlui/handle/1721.1/3791Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.creator | Seong, Jiehyun | - |
| dc.creator | Lee, Seok-Won | - |
| dc.creator | Jun, Shinae | - |
| dc.creator | Choi, Hyun-Goo | - |
| dc.creator | Laibinis, Paul E. | - |
| dc.date | 2003-12-08T16:02:44Z | - |
| dc.date | 2003-12-08T16:02:44Z | - |
| dc.date | 2003-01 | - |
| dc.date.accessioned | 2013-10-09T02:32:30Z | - |
| dc.date.available | 2013-10-09T02:32:30Z | - |
| dc.date.issued | 2013-10-09 | - |
| dc.identifier | http://hdl.handle.net/1721.1/3791 | - |
| dc.identifier.uri | http://koha.mediu.edu.my:8181/xmlui/handle/1721 | - |
| dc.description | We have investigated a series of molecular and polymeric approaches for generating adherent thin films that impart anti-fouling characteristics to oxide surfaces. These films incorporate oligo- or poly(ethylene glycol) moieties that are expressed in high density in the near-surface region. In our molecular approach, oligo(ethylene glycol)-terminated n-alkyl-trichlorosilanes, RO(CH₂CH₂O)₃(CH₂)₁₁SiCl₃, have been designed so to spontaneously adsorb onto oxide surfaces and produce densely packed films. Another strategy uses a surface initiated polymerization to generate reactive anchored polymer chains that are then chemically modified to incorporate oligo(ethylene glycol) units. Lastly, a comb copolymer comprising a poly(acrylic acid) backbone and different grafting ratios of a linear poly(ethylene oxide-r-propylene oxide) chain has been prepared that adsorbs onto surfaces and forms a poly(ethylene glycol)-exposing film in single step. These surface coatings provide varying levels of protein and cellular resistance that can be related to molecular-scale elements of their surface structure. | - |
| dc.description | Singapore-MIT Alliance (SMA) | - |
| dc.format | 444006 bytes | - |
| dc.format | application/pdf | - |
| dc.language | en_US | - |
| dc.relation | Molecular Engineering of Biological and Chemical Systems (MEBCS); | - |
| dc.subject | polymer coatings | - |
| dc.subject | protein adsorption | - |
| dc.subject | surface modification | - |
| dc.subject | thin films | - |
| dc.title | Self-Assembled Coatings for Controlling Biomolecular Adsorption on Surfaces | - |
| dc.type | Article | - |
| Appears in Collections: | MIT Items | |
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