Please use this identifier to cite or link to this item: http://dspace.mediu.edu.my:8181/xmlui/handle/123456789/5230
Title: Research: SELECTIVE DETERMINATION OF BAMBUTEROL HYDROCHLORIDE IN THE PRESENCE OF ITS ACTIVE METABOLITE TERBUTALINE
Keywords: Bambuterol hydrochloride
terbutaline
second derivative spectrophotometry
derivative-ratio
ratio subtraction
bivariate.
Issue Date: 30-May-2013
Publisher: Pharmacie Globale
Description: Stability-indicative determination of bambuterol hydrochloride (BH) in the presence of its degradation product (terbutaline), which is also the metabolite, is investigated. The degradation product has been isolated, via aciddegradation, characterized and elucidated. Selective quantification of BH, singly in bulk form, pharmaceutical formulations and/or in the presence of its major degradation product is demonstrated. The indication of stability has been undertaken under conditions likely to be expected at normal storage conditions. Among the spectrophotometric methods adopted for quantification are second derivative (2D), first derivative of ratio spectra (1DD), ratio subtraction and bivariate analysis.
URI: http://koha.mediu.edu.my:8181/jspui/handle/123456789/5230
Other Identifiers: http://www.pharmacie-globale.info/index.php?option=com_docman&task=doc_view&gid=167&tmpl=component&format=raw&Itemid=41
http://www.doaj.org/doaj?func=openurl&genre=article&issn=09768157&date=2011&volume=02&issue=06&spage=1
Appears in Collections:Health Sciences

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