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dc.creatorSánchez García, Isidro-
dc.creatorVoces, Felipe-
dc.creatorPérez-Mancera, P. A.-
dc.date2008-03-18T16:49:41Z-
dc.date2008-03-18T16:49:41Z-
dc.date2007-02-01-
dc.date.accessioned2017-01-31T01:00:48Z-
dc.date.available2017-01-31T01:00:48Z-
dc.identifierInternational Publication Number: WO 2007/012970 A1-
dc.identifierhttp://hdl.handle.net/10261/3252-
dc.identifier.urihttp://dspace.mediu.edu.my:8181/xmlui/handle/10261/3252-
dc.descriptionFiling Date: 2006-07-28.- Priority Data: EP 05076753.2 (2005-07-28).-
dc.descriptionThe invention relates to the graded expression level of SNAIL gene or its expression products, as a marker of the capacity of epithelial and mesenchymal tumours and/or cancers for disseminating to other tissues or organs. The invention further relates to a transgenic non-human mammal comprising in its genome a transgene that comprises a nucleic acid sequence encoding the SNAIL protein, and the use of SNAIL as a marker of epithelial and mesenchymal tumours and/or cancers as well as in DNA damage-based diseases In addition, the invention relates to the use of SNAIL as a therapeutic and diagnostic target for said pathologies.-
dc.descriptionPeer reviewed-
dc.format4417828 bytes-
dc.formatapplication/pdf-
dc.languageeng-
dc.rightsopenAccess-
dc.subjectSNAIL gene-
dc.subjectTumours-
dc.subjectTransgenic non-human mammal-
dc.subjectSNAIL protein-
dc.subjectCancer-
dc.subjectBiological Markers-
dc.titleGraded expression of SNAIL as marker of cancer development and DNA damage-based diseases-
dc.typePatente-
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