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http://dspace.mediu.edu.my:8181/xmlui/handle/10261/3252| Title: | Graded expression of SNAIL as marker of cancer development and DNA damage-based diseases |
| Keywords: | SNAIL gene Tumours Transgenic non-human mammal SNAIL protein Cancer Biological Markers |
| Description: | Filing Date: 2006-07-28.- Priority Data: EP 05076753.2 (2005-07-28). The invention relates to the graded expression level of SNAIL gene or its expression products, as a marker of the capacity of epithelial and mesenchymal tumours and/or cancers for disseminating to other tissues or organs. The invention further relates to a transgenic non-human mammal comprising in its genome a transgene that comprises a nucleic acid sequence encoding the SNAIL protein, and the use of SNAIL as a marker of epithelial and mesenchymal tumours and/or cancers as well as in DNA damage-based diseases In addition, the invention relates to the use of SNAIL as a therapeutic and diagnostic target for said pathologies. Peer reviewed |
| URI: | http://dspace.mediu.edu.my:8181/xmlui/handle/10261/3252 |
| Other Identifiers: | International Publication Number: WO 2007/012970 A1 http://hdl.handle.net/10261/3252 |
| Appears in Collections: | Digital Csic |
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