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http://dspace.mediu.edu.my:8181/xmlui/handle/10261/2831| Title: | Contribution of analytical microscopies to human neurodegenerative diseases research (PSP and AD). |
| Keywords: | Ferritinopathy Neuropathology Alzheimer Analytical microscopies NanoSIMS |
| Description: | PMID: 17897084 [PubMed - indexed for MEDLINE] Using analytical microscopies we have observed an increase of Fe(2+) iron-induced oxidative stress inside pathological ferritin (Ft). This finding, together with the presence of Ft in myelinated axons associated with oligodendrocyte processes and myelin sheet fraying, suggests that a dysfunction of ferritin (a ferritinopathy) may be the non-specific aging-dependent pathogenic event responsible for neurodegenerative disease. Peer reviewed |
| URI: | http://dspace.mediu.edu.my:8181/xmlui/handle/10261/2831 |
| Other Identifiers: | Mini Rev Med Chem. 2007 Sep;7(9):961-75 PMID: 17897084 http://hdl.handle.net/10261/2831 10.2174/138955707781662654 |
| Appears in Collections: | Digital Csic |
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