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| DC Field | Value | Language |
|---|---|---|
| dc.creator | Seiquer, Isabel | - |
| dc.creator | Navarro, María Pilar | - |
| dc.date | 2007-11-30T16:41:26Z | - |
| dc.date | 2007-11-30T16:41:26Z | - |
| dc.date | 2003-12-30 | - |
| dc.date.accessioned | 2017-01-31T00:59:15Z | - |
| dc.date.available | 2017-01-31T00:59:15Z | - |
| dc.identifier | Grasas y aceites 54 (4): 350-357 (2003) | - |
| dc.identifier | 1988-4214 | - |
| dc.identifier | http://hdl.handle.net/10261/2458 | - |
| dc.identifier.uri | http://dspace.mediu.edu.my:8181/xmlui/handle/10261/2458 | - |
| dc.description | The influence of the presence of brown products from the reaction between two oxidized lipids (4,5 (E)-epoxy-2(E)-heptenal, EH, and 4,5 (E)-epoxy-2 (E)-decenal, ED) and lysine (EH-L and ED-L) on zinc and calcium utilization was studied, and compared with a fructosyl-lysine mixture (F-L). Assays were carried out in Caco-2 cells grown in bicameral chambers. The Zn transported across the cell monolayer was significantly lower in the presence of the EH-L, ED-L and F-L samples, specially with EH-L. Significant decreases in Zn uptake were also observed, with no differences between samples. However, calcium transport was not modified. Thus, the assayed lipid-aminoacid brown products seem to have negative effects on Zn availability, whereas Ca availability appears to be unaffected. | - |
| dc.description | Se estudió la influencia de la presencia de productos obtenidos en la reacción de dos lípidos oxidados (4,5(E)-epoxy-2(E)- heptenal, EH, y 4,5(E)-epoxy-2(E)-decenal, ED) con el aminoácido lisina (EH-L y ED-L), sobre la absorción de zinc y calcio, comparándolos frente a una mezcla de fructosil-lisina (F-L). Los ensayos se realizaron con células Caco-2 sembradas en placas bicamerales. La adición de las muestras EH-L, ED-L y F-L al medio de cultivo supuso una reducción significativa en el Zn transportado a través de la monocapa de células, mucho más marcada ante la presencia de EH-L. También se redujo significativamente la captación celular de Zn, sin diferencias entre las distintas muestras ensayadas. Sin embargo, el transporte de Ca no se vio modificado. Por lo tanto, los productos pardos lípido-aminoacídicos ensayados parecen afectar negativamente la disponibilidad del Zn, sin tener efectos notables sobre la del Ca. | - |
| dc.description | Peer reviewed | - |
| dc.language | spa | - |
| dc.publisher | Consejo Superior de Investigaciones Científicas (España) | - |
| dc.rights | openAccess | - |
| dc.subject | Caco-2 cells | - |
| dc.subject | Calcium | - |
| dc.subject | Lipid-protein reaction | - |
| dc.subject | Oxidized lipids | - |
| dc.subject | Zinc | - |
| dc.title | Influencia de los productos de la reacción entre lípidos oxidados (4,5 (E)-epoxy-2(E)-heptenal y 4,5 (E)-epoxy- 2 (E) -decenal) y lisina sobre la utilización de zinc y calcio: ensayos en células Caco-2 | - |
| dc.title | Effects of oxidized lipids (4,5 (E)-epoxy-2(E)-heptenal and 4,5 (E)-epoxy-2 (E) -decenal) and lysine reaction products on zinc and calcium utilization: assays in Caco-2 cells | - |
| dc.type | Artículo | - |
| Appears in Collections: | Digital Csic | |
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